- MESNA binds acrolein (metabolite of ifosamide) that is irritant to urothelium
- Dexrasone iv is used with anthracycline extravasation
- Epirubicin and Doxorubicin are a red solution and can cause urine and sweat to appear pink after treatment.
- Methotrexate is yellow
- Mitomycin C is a light blue solution
- You can give vincristine, bleomycin and gemcitabine on day 8 as they have less myeloosuprresive effects on the pre-cursor cells.
- Gemcitabine and Fludarabine have synergy with cisplatin by inhibiting the repair of cisplatin adducts (by NER)
- 5-FU as a BOLUS affects RNA metabolism
- 5-FU as an INFUSION affects DNA metabolism
I've just got started with this blog. Give it time and I hope to create a really helpful resource for everyone out there sitting the exam. Please feel free to e-mail suggestions and 'killer' revision notes. Thanks. I would love to hear from you about this blog. Please post a comment.
A little disclaimer: I am doing this blog to hopefully help you when revising due to the very little available information about this exam. I am not affiliated with any organisation in doing this, completely unfunded and not being sponsored. I can not guarantee the accuracy of the information, but will do my best. If you think something is incorrect please let me know so we can all learn. Thanks
Friday, 1 July 2011
RANDOM PHARM FACTS
Posted by FRCR at 23:54